THE FACULTY
Meet Dr. Klein and Dr. Kassardjian
JEFFREY A. KLEIN M.D. – CURRICULUM VITAE
Dr. Jeffrey Klein – Curriculum Vitae
Office Address:
30280 Rancho Viejo Road
San Juan Capistrano, CA 92675
Office Telephone:
949-248-1632
FAX: 949-248-9339
Birth Date:
August 13, 1944
Place of Birth:
Los Angeles, California
Citizenship:
U.S.A.
Languages:
English, Spanish, French
Education
| School | Degree | Specialty | Dates |
|---|---|---|---|
| University of California, Riverside | BA | Mathematics | 1962-67 |
| Universite de Paris | Mathematics | 1967-68 | |
| University of California, San Diego | MA | Mathematics | 1968-71 |
| University of California, San Francisco | MD | Medicine | 1972-76 |
| University of California, Berkeley | MPH | Biostatistics | 1971-72 |
| University of California, Berkeley | Epidemiologys | 1976-77 | |
| University of California, Los Angeles | Internal Medicine Resident |
1977-80 | |
| University of London, Institute of Dermatology | Dermatology | Mar-Apr1980 | |
| All India Institute of Medical Sciences, New Delhi |
Dermatology | May-Jun1980 | |
| University of California, San Francisco | Clinical Pharmacology |
NIH Fellowship | 1980-81 |
| University of California, Irvine | Pharmacology | NIH Fellowship, Clinical | 1980-81 |
| University of California, Irvine | Dermatology Resident |
1981-84 |
Board Certification
| American Board of Internal Medicine | 1980 |
| American Board of Dermatology | 1984 |
| American Board of Cosmetic Surgery | 1989 |
| Other Certifications | Advanced Cardiac Life Support, Advanced Trauma Life Support |
| Present Activity | Private Practice: Dermatology, Dermatologic Surgery, and Cosmetic Surgery. |
| Previous Employment | California Emergency Physicians, Inc., Emergency Room Physician 1979-1985 |
Professional Societies
- American Academy of Dermatology
- American Society for Mohs Surgery
- American Society for Dermatologic Surgery
- Dermatology Foundation
- American Society of Anesthesiologists
- California Society of Anesthesiologists
- International Anesthesiology Research Society
- Orange County Medical Association (OCMA)
- California Medical Association
- American Medical Association
- Indian Association of Dermatologists Venereologists Leprologists AM/US/216/07)
Honors
American Society for Dermatologic Surgery President’s Award, 2004
“Outstanding & Unique Contributions to Dermatologic Surgery and The American Society for Dermatologic Surgery.”
Leadership In Professional Societies
- Founding Secretary: American Society for Mohs Surgery, 1994
- President – Orange County Society for Dermatology, 2003-2004
- Chairman (elect), Department of Dermatology, Hoag Hospital, Newport Beach, CA
University Advisory Committees
| 2005 to 2012 | The Dean’s Advisory Committee, College of Natural and Agricultural Sciences | University of California Riverside |
| 2005 to Present | University of California, Riverside Foundation, Board of Trustees | University of California, Riverside |
Recent Invited Guest Lectureships
| 2005 to Present | The Dean’s Advisory Committee, College of Natural and Agricultural Sciences | University of California |
| 2004 | British Association of Aesthetic Plastic Surgeons | Chester, England |
| 2005 | Brazilian Society for Dermatologic Surgery | Manaus, Brazil |
| 2006 | California Congress of Dermatology and Dermatologic Surgery | San Diego, CA |
| 2006 | Italian Society for Aesthetic Surgery | Rome |
| 2015 | The ASDS Leadership in Innovation Lectureship | Chicago, IL. |
| 2016 | The AAD Eugene J. Van Scott Award for Innovative Therapy of the Skin and Phillip Frost Leadership Lecture | Washington, DC |
National Television Interviews
| 1995 | 20/20 (ABC) |
| 1995 | Larry King Live |
Scientific Publications
| Klein, JA. | Optimal Statistical Techniques in Estimating Patient Compliance. | Preventive Med, | 1979 |
| Klein JA, Cole G, Barr RJ, Bartlow G, Fulwider C. | Paraffinoma of the Scalp | Arch Derm 121:382-385 | 1985 |
| Klein JA, Barr RJ. | Verrucous Hemangioma | J Pediat Derm, 2:191-193 | 1985 |
| McCullough JL, Peckham P, Klein J, Weinstein GD, Jenkins JJ. | Regulation of epidermal proliferation in mouse epidermis by combination of difluoromethyl ornithine (DFMO) and Methylglyoxal Bis(guanylhydrazone) (MGBG) | J Invest Derm 85:518-521 | 1985 |
| Klein JA, McCullough JL, Weinstein GD. | Topical tritiated thymidine for epidermal growth fraction determination. | J Invest Derm 86:406-409 | 1986 |
| Klein JA, Barr RA. | Diffuse lipomatosis and tuberous sclerosis. | Arch Derm 122:1298-1302 | 1986 |
| Klein JA. | The tumescent technique for liposuction surgery. | J Am Acad Cosmetic Surg 4:263-267 | 1987 |
| Klein JA. | Anesthesia for liposuction in dermatologic surgery. | J Derm Surg Oncol 14:1124-1132 | 1988 |
| Stewart JH, Cole GW, Klein JA. | Neutralized lidocaine with epinephrine for local anesthesia. | J Dermatol Surg Oncol 15:1081-1083 | 1989 |
| Klein JA. | Tumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction. | Derm Surg Oncol 16:248-263 | 1990 |
| Klein JA, Barr RJ. | Bannayan-Zonana Syndrome Associated with Lymphangiomyomatous lesions. | J Pediat Dermatol 7:48-53 | 1990 |
| Klein JA | The Tumescent Technique: Anesthesia and Modified Liposuction Technique. | Dermatol Clinics 8:425-437 | 1990 |
| Klein JA | Reply: Ethics of promoting patient safety and comity among surgical specialties. [letter] | Plast Reconstr Surg 95:603-604 | 1995 |
| Klein JA | Establishing a Dermatologic Surgicenter, Elson M, editor | Evaluation and Treatment of the Aging Face. Springer-Verlag, publishers, New York pp 255-260 | 1995 |
| Klein JA | Liposuction. Moy R, Lask G, editors | Principles and Techniques of Cutaneous Surgery. Mc Graw-Hill, New York, pp 529-542. | 1996 |
| Klein JA | Tumescent liposuction and improved postoperative care using Tumescent Liposuction Garments™. | Dermatol Clinics, 13:329-338 | 1995 |
| Klein JA | Tumescent Technique Chronicles: Local Anesthesia, Liposuction, and Beyond. | Dermatologic Surg. 21:449-457 | 1995 |
| Klein JA | Epitomes, Dermatology: Tumescent technique for local anesthesia. | West J Med 164:517 | 1996 |
| Klein JA | Tumescent liposuction with local anesthesia. | Principles and Techniques of Cutaneous Surgery. Lask GP, Moy RL editors. McGraw-Hill, New York, pp 529-542. | 1996 |
| Klein JA | Anesthesia for dermatologic cosmetic surgery. Coleman WP III, Hanke CW, Alt TH, Asken S, editors | Cosmetic Surgery of the Skin: Principles and Techniques. 2nd Edition. Philadelphia, B. C. Decker Inc. | 1997 |
| Klein JA | Two Standards of Care for Tumescent Liposuction. | Derm Surg J 24:1194-1195 | 1997 |
| Klein JA, Kassardjian N. | Lidocaine Toxicity with Tumescent Liposuction, a case report of probable drug interactions. | Derm Surg J 24:1169-1174 | 1997 |
| Klein JA | Tumescent Liposuction, Chapter 9, in Dzubow LM, editor | Cosmetic Dermatologic Surgery, Lippincott-Raven, Philadelphia, p163-169. | 1998 |
| Klein AW, Narins RS, Klein JA. | Tumescent Liposuction | Fitzpatrick’s Dermatology in General Medicine, 5th edition, McGraw Hill, New York, pp2967-2969. | 1999 |
| Klein JA. | Intravenous fluids and bupivacaine are contraindicated in tumescent liposuction (letter) | Plastic Reconstr Surg 102:2516-2518 | 1998 |
| Klein JA. | Anesthetic formulations of tumescent solutions. | Dermatologic Clinics, 17:751-759 | 1999 |
| Klein JA. | Post-tumescent liposuction care: open drainage and bimodal compression. | Dermatologic Clinics, 17:881-889 | 1999 |
| Klein JA. | Deaths related to liposuction. | N Eng J Med 341:1001. | 1999 |
| Klein JA. | Commentary: Fulton J. Modified Tumescent Liposuction. | Dermatol Surg 25:764-766 | 1999 |
| Klein JA. | Discussion: Perry AW, Petti C, Rankin M. Lidocaine is not necessary in liposuction. | Plast Reconstr Surg. 104: discussion 1903-6 | 1999 |
| Klein JA. | Antibacterial effects of tumescent lidocaine | Plast Reconstr Surg. 104:1934-6. | 1999 |
| Klein JA. | Tumescent Technique: Tumescent Anesthesia & Microcannular Liposuction. | Mosby, St. Louis, approx 500 pages | 2000 |
| Klein JA. | Pharmacology of Tumescent Liposuction. | Ch 21. pp 443-445. In Cosmetic Surgery: An Interdisciplinary Approach, Narins RS editor, Marcel Dekker, New York | 2001 |
| Klein JA. | Liposuction Using Dilute Local Anesthesia: Counterpoint. | Dermatol Surg 29:1146-7 | 2003 |
| Klein JA. | Is Tumescent Liposuction Safe?, Baran R, Maibach HI, Editors | Textbook of Cosmetic Surgery, 3rd ed. Chapter 64, pages 621-628, Taylor&Francis Publishers, London&New York (ISBN 1-84184-311-3) | 2005 |
| Kucera IJ, Lambert TJ, Klein JA, Watkins RG, Hoover JM, Kaye AD. | Liposuction: contemporary issues for the anesthesiologist. | J Clin Anesth. 18:379-87 | 2006 |
| Wanner M, Mihm MC, Jr, Farinelli WA, Doukas A, Zurakowski D, Piris A, Avram MM, Klein JA, Anderson RR. | Use of Photodynamic Therapy and Sterile Water to Target Adipose Tissue. | Dermatol Surg. 41:803-11. | 2015 |
| Klein JA, Jeske DR. | Estimated maximum safe dosage of tumescent lidocaine. | Anesth Analg, in press. | 2015 |
| Klein JA, Langman LJ. | Tumescent Infiltration Drug Delivery: Pharmacokinetics of Subcutaneous Antibiotics for Prevention of Surgical Site Infection and Systemic Inflammation. | Submitted to Anesth Analg | 2015 |
| Klein JA, Zand AR, Klein LEW, Klein PA, vanZandt J | invivoPFT: digital photographic analysis measurement of bleeding volume during a Ivy Bleeding Time test | Submitted to Anesth Analg | (ready for submission) |
Current Research
Tumescent Infiltration of Antibiotics for Surgical Site Infection, Thrombosis and Sepsis Prophylaxis:
A Multicenter Open Label Randomized Clinical Trial
Double-Blind Controlled Randomized Clinical Trial of Laser Liposuction
Bleeding Volume Test: A Double-Blind Crossover Randomized Clinical Trial of invivoPFT, a Platelet Function Test.
Tumescent Lidocaine for Platelet Function Inhibition
Commercial Interests Related to Medicine & Dermatologic Surgery
| HK Surgical, Inc | Surgical Supplies for TumescentAnesthesia & Liposuction | www.hksurgical.com |
| Liposuction.com | Information for Prospective Patients@ Surgeon Directory | www.liposuction.com |
| Liposuction101 | Hands-On Teaching (27 Hours CME) | www.liposuction101.com |
| Newport Beach Liposuction | Laser and tumescent liposuctionsurgery in Newport Beach | www.jeffreykleinliposuction.com |
United States Patents (www.uspto.gov)
U.S. PAT. NO. Title
5,052,999 Liposuction method and apparatus
5,682,607 Skin appliqué to provide protection from ultraviolet light
D387,167 Liposuction patient positioning support (Design Patent)
5,817,050 Liposuction cannula
5,950,238 Post-liposuction breast compression garment and method for edema reduction
6,032,669 Positioning pillow for approximating anatomic position in lateral decubitus position
6,162,960 Compression sponge for wound care
6,676,677 Liposuction cannula with abrading apertures
6,849,775 Method of forming absorbent pad using precut overlay (2005)
7,364,545 Method of measuring bleeding volume (2008)
7,572,613 Drug delivery system for accelerated subcutaneous absorption (2009)
7,914,504 B2 Infiltration Cannula (March 29, 2011)
8,105,310 B2 Infiltration Cannula (Jan. 31, 2012)
8,118,572 Peristaltic pump tubing with stopper and cooperative roller assembly housing having no moving parts (Feb 21, 2012)
8,167,866 B2 Drug Delivery System For Accelerated Subcutaneous Absorption (May 1, 2012)
8,246,587 B2 Infiltration Cannula (Aug 21, 2012)
8,417,544 B2 Research Collaboration System (April 9, 2013) http://www.google.com/patents/US8417544
8,506,551 B2 Infiltration Cannula (Aug13, 2013)
8,512,292 B2 Infiltration Cannula (Aug 20, 2013)
8,515,006 B2 Fiducial System for Mammography (Aug 20, 2013)
8,529,541 B2 Infiltration Cannula (Sept 10, 2013)
8,579,612 B2 Peristaltic pump tubing with stopper and cooperative roller assembly housing having no moving parts
(Nov 12, 2013)
8,923,477 B2 Fiducial System for Mammography (Aug 20, 2013)
8,957060 B2 Tumescent Antibiotic Solution (Feb. 17, 2015)
US 2012/0322783 A1 Patent Application Publication: Tumescent Antibiotic Solution (Dec 20, 2012)
Principal Investigator for Clinical Trials Registered on www.ClinicalTrials.Gov
ClinicalTrials.gov Identifier
NCT00977028 TLA Peak Tumescent Lidocaine Maximum Safe mg/kg Dosage
Accepted for publication in Anesthesia & Analgesia 2015
NCT01046981 TAD Tumescent Antibiotic Delivery: Pharmacokinetic Evidence
For Improved Surgical Site Infection Prevention
Results to be submitted for publication 2015
NCT01047722 BVT-ASA In-Vivo Bleeding Volume Test for Platelet-Aspirin Interaction
NCT01463280 BA-LidoLipo Tumescent Lidocaine Effects on Platelet Function Following
Liposuction Surgical Trauma: A Prospective Controlled Dosage-
Response Phase I Clinical Trial
NCT02503904 TISSITS Tumescent Infiltration of Antibiotics for Surgical Site Infection, Thrombosis
and Sepsis Prophylaxis: A Multicenter Open Label Randomized Clinical Trial
Pending TIA4PHN Tumescent Infiltration Acyclovir for Post Herpetic Neuralgia Prophylaxis:
A Multicenter Open Label Randomized Clinical Trial