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Meet Dr. Klein and Dr. Kassardjian



Dr. Jeffrey Klein – Curriculum Vitae


Office Address:
30280 Rancho Viejo Road
San Juan Capistrano, CA 92675

Office Telephone:
FAX: 949-248-9339

Birth Date:
August 13, 1944

Place of Birth:
Los Angeles, California


English, Spanish, French


School Degree Specialty Dates
University of California, Riverside BA Mathematics 1962-67
Universite de Paris   Mathematics 1967-68
University of California, San Diego MA Mathematics 1968-71
University of California, San Francisco MD Medicine 1972-76
University of California, Berkeley MPH Biostatistics 1971-72
University of California, Berkeley   Epidemiologys 1976-77
University of California, Los Angeles   Internal Medicine
University of London, Institute of Dermatology Dermatology   Mar-Apr1980
All India Institute of Medical Sciences,
New Delhi
Dermatology   May-Jun1980
University of California, San Francisco Clinical
NIH Fellowship 1980-81
University of California, Irvine Pharmacology NIH Fellowship, Clinical 1980-81
University of California, Irvine Dermatology

Board Certification

American Board of Internal Medicine 1980
American Board of Dermatology 1984
American Board of Cosmetic Surgery 1989
Other Certifications Advanced Cardiac Life Support,
Advanced Trauma Life Support
Present Activity Private Practice: Dermatology, Dermatologic
Surgery, and Cosmetic Surgery.
Previous Employment California Emergency Physicians, Inc.,
Emergency Room Physician 1979-1985

Professional Societies

  • American Academy of Dermatology
  • American Society for Mohs Surgery
  • American Society for Dermatologic Surgery
  • Dermatology Foundation
  • American Society of Anesthesiologists
  • California Society of Anesthesiologists
  • International Anesthesiology Research Society
  • Orange County Medical Association (OCMA)
  • California Medical Association
  • American Medical Association
  • Indian Association of Dermatologists Venereologists Leprologists AM/US/216/07)


American Society for Dermatologic Surgery President’s Award,  2004
“Outstanding & Unique Contributions to Dermatologic Surgery and The American Society for Dermatologic Surgery.”

Leadership In Professional Societies

  • Founding Secretary: American Society for Mohs Surgery, 1994
  • President – Orange County Society for Dermatology, 2003-2004
  • Chairman (elect), Department of Dermatology, Hoag Hospital, Newport Beach, CA

University Advisory Committees

2005 to 2012 The Dean’s Advisory Committee, College of Natural and Agricultural Sciences University of California Riverside
2005 to Present University of California, Riverside Foundation, Board of Trustees University of California, Riverside

Recent Invited Guest Lectureships

2005 to Present The Dean’s Advisory Committee, College of Natural and Agricultural Sciences University of California
2004 British Association of Aesthetic Plastic Surgeons Chester, England
2005 Brazilian Society for Dermatologic Surgery Manaus, Brazil
2006 California Congress of Dermatology and Dermatologic Surgery San Diego, CA
2006 Italian Society for Aesthetic Surgery Rome
2015 The ASDS Leadership in Innovation Lectureship Chicago, IL.
2016 The AAD Eugene J. Van Scott Award for Innovative Therapy of the Skin and Phillip Frost Leadership Lecture Washington, DC

National Television Interviews

1995 20/20 (ABC)
1995 Larry King Live

Scientific Publications

Klein, JA. Optimal Statistical Techniques in Estimating Patient Compliance. Preventive Med, 1979
Klein JA, Cole G, Barr RJ, Bartlow G, Fulwider C. Paraffinoma of the Scalp Arch Derm 121:382-385 1985
Klein JA, Barr RJ. Verrucous Hemangioma J Pediat Derm, 2:191-193 1985
McCullough JL, Peckham P, Klein J, Weinstein GD, Jenkins JJ. Regulation of epidermal proliferation in mouse epidermis by combination of difluoromethyl ornithine (DFMO) and Methylglyoxal Bis(guanylhydrazone) (MGBG) J Invest Derm 85:518-521 1985
Klein JA, McCullough JL, Weinstein GD. Topical tritiated thymidine for epidermal growth fraction determination. J Invest Derm 86:406-409 1986
Klein JA, Barr RA. Diffuse lipomatosis and tuberous sclerosis. Arch Derm 122:1298-1302 1986
Klein JA. The tumescent technique for liposuction surgery. J Am Acad Cosmetic Surg 4:263-267 1987
Klein JA. Anesthesia for liposuction in dermatologic surgery. J Derm Surg Oncol 14:1124-1132 1988
Stewart JH, Cole GW, Klein JA. Neutralized lidocaine with epinephrine for local anesthesia. J Dermatol Surg Oncol 15:1081-1083 1989
Klein JA. Tumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction. Derm Surg Oncol 16:248-263 1990
Klein JA, Barr RJ. Bannayan-Zonana Syndrome Associated with Lymphangiomyomatous lesions. J Pediat Dermatol 7:48-53 1990
Klein JA The Tumescent Technique: Anesthesia and Modified Liposuction Technique. Dermatol Clinics 8:425-437 1990
Klein JA Reply: Ethics of promoting patient safety and comity among surgical specialties. [letter] Plast Reconstr Surg 95:603-604 1995
Klein JA Establishing a Dermatologic Surgicenter, Elson M, editor Evaluation and Treatment of the Aging Face. Springer-Verlag, publishers, New York pp 255-260 1995
Klein JA Liposuction. Moy R, Lask G, editors Principles and Techniques of Cutaneous Surgery. Mc Graw-Hill, New York, pp 529-542. 1996
Klein JA Tumescent liposuction and improved postoperative care using Tumescent Liposuction Garments™. Dermatol Clinics, 13:329-338 1995
Klein JA Tumescent Technique Chronicles: Local Anesthesia, Liposuction, and Beyond. Dermatologic Surg. 21:449-457 1995
Klein JA Epitomes, Dermatology: Tumescent technique for local anesthesia. West J Med 164:517 1996
Klein JA Tumescent liposuction with local anesthesia. Principles and Techniques of Cutaneous Surgery. Lask GP, Moy RL editors. McGraw-Hill, New York, pp 529-542. 1996
Klein JA Anesthesia for dermatologic cosmetic surgery. Coleman WP III, Hanke CW, Alt TH, Asken S, editors Cosmetic Surgery of the Skin: Principles and Techniques. 2nd Edition. Philadelphia, B. C. Decker Inc. 1997
Klein JA Two Standards of Care for Tumescent Liposuction. Derm Surg J 24:1194-1195 1997
Klein JA, Kassardjian N. Lidocaine Toxicity with Tumescent Liposuction, a case report of probable drug interactions. Derm Surg J 24:1169-1174 1997
Klein JA Tumescent Liposuction, Chapter 9, in Dzubow LM, editor Cosmetic Dermatologic Surgery, Lippincott-Raven, Philadelphia, p163-169. 1998
Klein AW, Narins RS, Klein JA. Tumescent Liposuction Fitzpatrick’s Dermatology in General Medicine, 5th edition, McGraw Hill, New York, pp2967-2969. 1999
Klein JA. Intravenous fluids and bupivacaine are contraindicated in tumescent liposuction (letter) Plastic Reconstr Surg 102:2516-2518 1998
Klein JA. Anesthetic formulations of tumescent solutions. Dermatologic Clinics, 17:751-759 1999
Klein JA. Post-tumescent liposuction care: open drainage and bimodal compression. Dermatologic Clinics, 17:881-889 1999
Klein JA. Deaths related to liposuction. N Eng J Med 341:1001. 1999
Klein JA. Commentary: Fulton J. Modified Tumescent Liposuction. Dermatol Surg 25:764-766 1999
Klein JA. Discussion: Perry AW, Petti C, Rankin M. Lidocaine is not necessary in liposuction. Plast Reconstr Surg. 104: discussion 1903-6 1999
Klein JA. Antibacterial effects of tumescent lidocaine Plast Reconstr Surg. 104:1934-6. 1999
Klein JA. Tumescent Technique: Tumescent Anesthesia & Microcannular Liposuction. Mosby, St. Louis, approx 500 pages 2000
Klein JA. Pharmacology of Tumescent Liposuction. Ch 21. pp 443-445. In Cosmetic Surgery: An Interdisciplinary Approach, Narins RS editor, Marcel Dekker, New York 2001
Klein JA. Liposuction Using Dilute Local Anesthesia: Counterpoint. Dermatol Surg 29:1146-7 2003
Klein JA. Is Tumescent Liposuction Safe?, Baran R, Maibach HI, Editors Textbook of Cosmetic Surgery, 3rd ed. Chapter 64, pages 621-628, Taylor&Francis Publishers, London&New York (ISBN 1-84184-311-3) 2005
Kucera IJ, Lambert TJ, Klein JA, Watkins RG, Hoover JM, Kaye AD. Liposuction: contemporary issues for the anesthesiologist. J Clin Anesth. 18:379-87 2006
Wanner M, Mihm MC, Jr, Farinelli WA, Doukas A, Zurakowski D, Piris A, Avram MM, Klein JA, Anderson RR. Use of Photodynamic Therapy and Sterile Water to Target Adipose Tissue. Dermatol Surg. 41:803-11. 2015
Klein JA, Jeske DR. Estimated maximum safe dosage of tumescent lidocaine. Anesth Analg, in press. 2015
Klein JA, Langman LJ. Tumescent Infiltration Drug Delivery: Pharmacokinetics of Subcutaneous Antibiotics for Prevention of Surgical Site Infection and Systemic Inflammation. Submitted to Anesth Analg 2015
Klein JA, Zand AR, Klein LEW, Klein PA, vanZandt J invivoPFT: digital photographic analysis measurement of bleeding volume during a Ivy Bleeding Time test Submitted to Anesth Analg (ready for submission)

Current Research

Tumescent Infiltration of Antibiotics for Surgical Site Infection, Thrombosis and Sepsis Prophylaxis:

A Multicenter Open Label Randomized Clinical Trial

Double-Blind Controlled Randomized Clinical Trial of Laser Liposuction

Bleeding Volume Test: A Double-Blind Crossover Randomized Clinical Trial of invivoPFT, a Platelet Function Test.

Tumescent Lidocaine for Platelet Function Inhibition

Commercial Interests Related to Medicine & Dermatologic Surgery

HK Surgical, Inc Surgical Supplies for TumescentAnesthesia & Liposuction Information for Prospective Patients@ Surgeon Directory
Liposuction101 Hands-On Teaching (27 Hours CME)
Newport Beach Liposuction Laser and tumescent liposuctionsurgery in Newport Beach

United States Patents (

U.S. PAT. NO.                       Title

5,052,999          Liposuction method and apparatus

5,682,607          Skin appliqué to provide protection from ultraviolet light

D387,167          Liposuction patient positioning support (Design Patent)

5,817,050          Liposuction cannula

5,950,238          Post-liposuction breast compression garment and method for edema reduction

6,032,669          Positioning pillow for approximating anatomic position in lateral decubitus position

6,162,960          Compression sponge for wound care

6,676,677          Liposuction cannula with abrading apertures

6,849,775          Method of forming absorbent pad using precut overlay (2005)

7,364,545          Method of measuring bleeding volume (2008)

7,572,613          Drug delivery system for accelerated subcutaneous absorption (2009)

7,914,504 B2     Infiltration Cannula (March 29, 2011)

8,105,310 B2     Infiltration Cannula (Jan. 31, 2012)

8,118,572          Peristaltic pump tubing with stopper and cooperative roller assembly housing having no moving parts (Feb 21, 2012)

8,167,866 B2     Drug Delivery System For Accelerated Subcutaneous Absorption (May 1, 2012)

8,246,587 B2     Infiltration Cannula (Aug 21, 2012)

8,417,544 B2     Research Collaboration System (April 9, 2013)

8,506,551 B2     Infiltration Cannula (Aug13, 2013)

8,512,292 B2     Infiltration Cannula (Aug 20, 2013)

8,515,006 B2     Fiducial System for Mammography (Aug 20, 2013)

8,529,541 B2     Infiltration Cannula (Sept 10, 2013)

8,579,612 B2     Peristaltic pump tubing with stopper and cooperative roller assembly housing having no moving parts

(Nov 12, 2013)

8,923,477 B2     Fiducial System for Mammography (Aug 20, 2013)

8,957060 B2      Tumescent Antibiotic Solution (Feb. 17, 2015)

US 2012/0322783 A1 Patent Application Publication: Tumescent Antibiotic Solution (Dec 20, 2012)

Principal Investigator for Clinical Trials Registered on www.ClinicalTrials.Gov Identifier

NCT00977028                     TLA Peak              Tumescent Lidocaine Maximum Safe mg/kg Dosage

Accepted for publication in Anesthesia & Analgesia 2015


NCT01046981                     TAD                        Tumescent Antibiotic Delivery: Pharmacokinetic Evidence

For Improved Surgical Site Infection Prevention

Results to be submitted for publication 2015


NCT01047722                     BVT-ASA              In-Vivo Bleeding Volume Test for Platelet-Aspirin Interaction


NCT01463280                     BA-LidoLipo        Tumescent Lidocaine Effects on Platelet Function Following

Liposuction Surgical Trauma: A Prospective Controlled Dosage-

Response Phase I Clinical Trial


NCT02503904                 TISSITS                  Tumescent Infiltration of Antibiotics for Surgical Site Infection, Thrombosis

and Sepsis Prophylaxis: A Multicenter Open Label Randomized Clinical Trial


Pending                               TIA4PHN              Tumescent Infiltration Acyclovir for Post Herpetic Neuralgia Prophylaxis:

A Multicenter Open Label Randomized Clinical Trial

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